zhpsЖурнал прикладной спектроскопииZhurnal Prikladnoii Spektroskopii0514-7506B. I. Stepanov Institute of Physics of the National Academy of Scienceszhps-492Research ArticleСтатьиИММУНОАНАЛИЗ ДВУХ ЦИТОКИНОВ В ДЕСНЕВОЙ ЖИДКОСТИ ЧЕЛОВЕКА ПРИ ЗАБОЛЕВАНИЯХ ПАРОДОНТА НА ОСНОВЕ СПЕКТРОСКОПИИ ПОВЕРХНОСТНО-УСИЛЕННОГО КОМБИНАЦИОННОГО РАССЕЯНИЯSURFACE-ENHANCED RAMAN SCATTERING-BASED IMMUNOASSAY OF TWO CYTOKINES IN HUMAN GINGIVAL CREVICULAR FLUID OF PERIODONTAL DISEASEYangH.YangH.

Чэнду, 610041

Chengdu, 610041

ZhangM. L.ZhangM. L.

Чунцин, 400010

Chongqing, 400010

YaoL. H.YaoL. H.

Хэнань, 450000

Henan, 450000

ZhouM.ZhouM.

Чунцин, 400017

Chongqing, 400017

WangQ.WangQ.

Чэнду, 610041

State Key Laboratory of Oral Diseases

Chengdu, 610041

ChenYuChenYu

Чэнду, 610041

State Key Laboratory of Oral Diseases

Chengdu, 610041

DingY.DingY.

Чэнду, 610041

State Key Laboratory of Oral Diseases

Chengdu, 610041

jessie.yh@163.comПервая народная больница ЧэндуChengdu First People’s HospitalЧунцинская стоматологическая клиникаChongqing Share dent ClinicПервая больница университета ЧжэнчжоуThe First Affiliated Hospital of Zhengzhou UniversityСтоматологическая больница Чунцинского медицинского университетаStomatological Hospital of Chongqing Medical UniversityНациональный центр клинических исследований заболеваний полости рта, Западно-Китайская стоматологическая больница, Университет СычуаньNational Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University201917032020866968975Copyright © Yang H., Zhang M.L., Yao L.H., Zhou M., Wang Q., Chen Y., Ding Y., 20202020Yang H., Zhang M.L., Yao L.H., Zhou M., Wang Q., Chen Y., Ding Y.Yang H., Zhang M.L., Yao L.H., Zhou M., Wang Q., Chen Y., Ding Y.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://zhps.ejournal.by/jour/article/view/492пародонтитдесневая кревикулярная жидкостьгигантское комбинационное рассеяниецитокинывоспалениеperiodontal diseasegingival crevicular fluidsurface-enhanced Raman scatteringcytokinesinflammationThe work was performed with financial support from the National Key Basic Research and Development Program (grant No.2013CBA01700), National Nature Science Foundation of China (grant No. 81371149), and Chengdu Medical Research Project (No. 2018026).The work was performed with financial support from the National Key Basic Research and Development Program (grant No.2013CBA01700), National Nature Science Foundation of China (grant No. 81371149), and Chengdu Medical Research Project (No. 2018026).ReferencesB. L. Pihlstrom, B. S. Michalowicz, N. W. Johnson, Lancet, 366, 1809–1820 (2005).B. L. Pihlstrom, B. S. Michalowicz, N. W. Johnson, Lancet, 366, 1809–1820 (2005).G. C. Armitage, Periodontol. 2000, 34, 109–119 (2004).G. C. Armitage, Periodontol. 2000, 34, 109–119 (2004).H. Ito, Y. Numabe, S. Hashimoto, S. Sekino, E. Murakashi, H. Ishiguro, J. Periodontol., 87, 1314–1319 (2016).H. Ito, Y. Numabe, S. Hashimoto, S. Sekino, E. Murakashi, H. Ishiguro, J. Periodontol., 87, 1314–1319 (2016).Q. Zhang, B. Chen, D. Zhu, F. Yan, Arch. Oral. Biol., 72, 92–98 (2016).Q. Zhang, B. Chen, D. Zhu, F. Yan, Arch. Oral. Biol., 72, 92–98 (2016).O. Cakmak, Z. Tasdemir, C. A. Aral, S. Dundar, H. B. Koca, J. Clin. Periodontol., 43, 1024–1031 (2016).O. Cakmak, Z. Tasdemir, C. A. Aral, S. Dundar, H. B. Koca, J. Clin. Periodontol., 43, 1024–1031 (2016).J. Liukkonen, U. K. Gürsoy, P. J. Pussinen, A. L. Suominen, E. Könönen, J. Periodontol., 87, 1484–1491 (2016).J. Liukkonen, U. K. Gürsoy, P. J. Pussinen, A. L. Suominen, E. Könönen, J. Periodontol., 87, 1484–1491 (2016).M. Kuboniwa, A. Sakanaka, E. Hashino, T. Bamba, E. Fukusaki, A. Amano, J. Dent. Res., 95, 1381–1386 (2016).M. Kuboniwa, A. Sakanaka, E. Hashino, T. Bamba, E. Fukusaki, A. Amano, J. Dent. Res., 95, 1381–1386 (2016).R. C. Page, J. Periodontol., 63, 356–366 (1992).R. C. Page, J. Periodontol., 63, 356–366 (1992).J. Gamonal, A. Acevedo, A. Bascones, O. Jorge, J. Periodontol., 71, 1535–1545 (2000).J. Gamonal, A. Acevedo, A. Bascones, O. Jorge, J. Periodontol., 71, 1535–1545 (2000).N. R. Isola, D. L. Stokes, T. Vo-Dinh, Anal. Chem., 70, 1352 (1998).N. R. Isola, D. L. Stokes, T. Vo-Dinh, Anal. Chem., 70, 1352 (1998).W. Ren, Y. Fang, E. Wang, ACS Nano, 5, 6425–6433 (2011).W. Ren, Y. Fang, E. Wang, ACS Nano, 5, 6425–6433 (2011).M. Y. Sha, H. Xu, M. J. Natan, R. Cromer, J. Am. Chem. Soc., 130, 17214–17215 (2008).M. Y. Sha, H. Xu, M. J. Natan, R. Cromer, J. Am. Chem. Soc., 130, 17214–17215 (2008).Y. C. Cao, R. Jin, C. A. Mirkin, Science, 297, 1536 (2002).Y. C. Cao, R. Jin, C. A. Mirkin, Science, 297, 1536 (2002).Y. Chen, H. Cheng, K. Tram, S. Zhang, Y. Zhao, L. Han, Z. Chen, S. Huan, Analyst, 138, 2624–26231 (2013).Y. Chen, H. Cheng, K. Tram, S. Zhang, Y. Zhao, L. Han, Z. Chen, S. Huan, Analyst, 138, 2624–26231 (2013).L. Wu, Z. Wang, S. Zong, H. Chen, C. Wang, S. Xu, Y. Cui, Analyst, 138, 3450–3456 (2013).L. Wu, Z. Wang, S. Zong, H. Chen, C. Wang, S. Xu, Y. Cui, Analyst, 138, 3450–3456 (2013).E. Papadopoulou, S. E. Bell, Chemistry, 18, 5394 (2012).E. Papadopoulou, S. E. Bell, Chemistry, 18, 5394 (2012).G. F. Wang, R. J. Lipert, M. Jain, S. Kaur, S. Chakraboty, M. P. Torres, S. K. Batra, R. E. Brand, M. D. Porter, Anal.Chem., 83, 2554–2561 (2011).G. F. Wang, R. J. Lipert, M. Jain, S. Kaur, S. Chakraboty, M. P. Torres, S. K. Batra, R. E. Brand, M. D. Porter, Anal.Chem., 83, 2554–2561 (2011).H. Hwang, H. Chon, J. Choo, J. K. Park, Anal. Chem., 82, 7603–7610 (2010).H. Hwang, H. Chon, J. Choo, J. K. Park, Anal. Chem., 82, 7603–7610 (2010).V. L. Schmit, R. Martoglio, K. T. Carron, Anal. Chem., 84, 4233–4236 (2012).V. L. Schmit, R. Martoglio, K. T. Carron, Anal. Chem., 84, 4233–4236 (2012).P. V. Lee, D. Meisel, J. Phys. Chem., 86, 3391–3395 (1982).P. V. Lee, D. Meisel, J. Phys. Chem., 86, 3391–3395 (1982).C. Jehn, B. Kustner, P. Adam, A. Marx, P. Strobel, C. Schmuck, S. Schlucker, Phys. Chem. Chem. Phys., 11, 7499–7504 (2009).C. Jehn, B. Kustner, P. Adam, A. Marx, P. Strobel, C. Schmuck, S. Schlucker, Phys. Chem. Chem. Phys., 11, 7499–7504 (2009).E. Papathanasiou, F. Teles, T. Griffin, E. Arguello, M. Finkelman, J. Hanley, J. Periodont. Res., 49, 55–61 (2014).E. Papathanasiou, F. Teles, T. Griffin, E. Arguello, M. Finkelman, J. Hanley, J. Periodont. Res., 49, 55–61 (2014).Y. G. Sun, Y. D. Yin, B. T. Mayers, T. Herricks, Y. N. Xia, Chem. Mater., 14, 4736–4745 (2002).Y. G. Sun, Y. D. Yin, B. T. Mayers, T. Herricks, Y. N. Xia, Chem. Mater., 14, 4736–4745 (2002).M. D. Porter, R. J. Lipert, L. M. Sioperko, G. Wang, R. Narayanan, Chem. Soc. Rev., 37, 1001–1011 (2008).M. D. Porter, R. J. Lipert, L. M. Sioperko, G. Wang, R. Narayanan, Chem. Soc. Rev., 37, 1001–1011 (2008).Y. Wang, M. Salehi, M. Schütz, K. Rudi, S. Schlücker, Analyst, 138, 1764–1771 (2013).Y. Wang, M. Salehi, M. Schütz, K. Rudi, S. Schlücker, Analyst, 138, 1764–1771 (2013).

The authors declare that there are no conflicts of interest present.