<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">zhps</journal-id><journal-title-group><journal-title xml:lang="ru">Журнал прикладной спектроскопии</journal-title><trans-title-group xml:lang="en"><trans-title>Zhurnal Prikladnoii Spektroskopii</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0514-7506</issn><publisher><publisher-name>B. I. Stepanov Institute of Physics of the National Academy of Sciences</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">zhps-75</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>МЕТОД ВЫДЕЛЕНИЯ КРОВЕНОСНЫХ СОСУДОВ НА ТРЕХЦВЕТНЫХ ИЗОБРАЖЕНИЯХ БИОТКАНЕЙ</article-title><trans-title-group xml:lang="en"><trans-title>METHOD FOR SEPARATION OF BLOOD VESSELS ON THE THREE-COLOR IMAGES OF BIOLOGICAL TISSUES</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лысенко</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Lisenko</surname><given-names>S. A.</given-names></name></name-alternatives><email xlink:type="simple">lisenko@bsu.by</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Белорусский государственный университет</institution></aff><aff xml:lang="en"><institution>Belarusian State University</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>10</day><month>03</month><year>2020</year></pub-date><volume>84</volume><issue>3</issue><fpage>419</fpage><lpage>427</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Лысенко С.А., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Лысенко С.А.</copyright-holder><copyright-holder xml:lang="en">Lisenko S.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://zhps.ejournal.by/jour/article/view/75">https://zhps.ejournal.by/jour/article/view/75</self-uri><abstract><p>Разработана новая технология улучшения видимости кровеносных сосудов на изображениях тканей полых органов человека (пищеварительного тракта и дыхательной системы), использующая связь цветовых компонент изображения с рассеивающими свойствами ткани и содержанием в ней гемоглобина. Предложен статистический оператор преобразования трехцветного изображения ткани в параметрическую карту, объективно характеризующую концентрацию гемоглобина в ткани независимо от условий освещения и съемки. Приведен алгоритм получения параметров преобразования для съемочных систем с известными спектральными характеристиками. Синтезировано изображение многослойной многократно рассеивающей среды, моделирующей бронхиальную ткань, и на его основе оценена эффективность предложенного преобразования. Показано, что оно позволяет почти на два порядка повысить контраст сосудов и существенно улучшить четкость отображения их границ, практически полностью устранить влияние фона и неравномерной освещенности среды по сравнению с исходным изображением.</p></abstract><trans-abstract xml:lang="en"><p>A new technology has been developed to improve the visibility of blood vessels on the images of biological tissues based on the relation between image color components, scattering properties of the tissue and hemoglobin content in it. A statistical operator was presented to convert a three-color image of tissue into the parametric map objectively characterizing the concentration of hemoglobin in the tissue regardless of the illumination and shooting conditions. An algorithm for obtaining the conversion parameters for imaging systems with known spectral characteristics was presented. An image of a multilayer multiple-scattering medium modeling bronchial tissue was synthesized, and the efficiency of the proposed conversion was evaluated on its basis. It was shown that the conversion makes it possible to increase the contrast of blood vessels by almost two orders and significantly improve the clarity of the display of their borders, to almost completely eliminate the influence of background and non-uniform illumination of the medium in comparison with the original image.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>биологическая ткань</kwd><kwd>кровеносные сосуды</kwd><kwd>трехцветные изображения</kwd><kwd>многократное рассеяние</kwd><kwd>гемоглобиновый индекс</kwd><kwd>локальный диаметр сосуда</kwd><kwd>параметрические карты</kwd><kwd>biological tissue</kwd><kwd>blood vessels</kwd><kwd>three-colored images</kwd><kwd>multiple scattering</kwd><kwd>hemoglobin index</kwd><kwd>local vessel diameter</kwd><kwd>parametric maps</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">K. Yao, T. Oishi, T. Matsui, T. Yao, A. Iwashita. Gastrointest. Endоsc., 56, N 2 (2002) 279-284</mixed-citation><mixed-citation xml:lang="en">K. Yao, T. Oishi, T. Matsui, T. Yao, A. Iwashita. Gastrointest. Endоsc., 56, N 2 (2002) 279-284</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Y. Ezoe, M. Muto, N. Uedo, H. Doyama, K. Yao, I. Oda, K. Kaneko, Y. Kawahara, C. Yokoi, Y. Sugiura, H. Ishikawa, Y. Takeuchi, Y. Kaneko, Y. Saito. Gastroenterology, 141, N 6 (2011) 2017-2025</mixed-citation><mixed-citation xml:lang="en">Y. Ezoe, M. Muto, N. Uedo, H. Doyama, K. Yao, I. Oda, K. Kaneko, Y. Kawahara, C. Yokoi, Y. Sugiura, H. Ishikawa, Y. Takeuchi, Y. Kaneko, Y. Saito. Gastroenterology, 141, N 6 (2011) 2017-2025</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">О. А. Бунцева, З. В. Галкова, Р. В. Плахов, К. Ю. Эрендженова, Е. Д. Федоров, В. В. Мизгулин, Р. М. Кадушников. ЭиКГ, 110, № 10 (2014) 88-96</mixed-citation><mixed-citation xml:lang="en">О. А. Бунцева, З. В. Галкова, Р. В. Плахов, К. Ю. Эрендженова, Е. Д. Федоров, В. В. Мизгулин, Р. М. Кадушников. ЭиКГ, 110, № 10 (2014) 88-96</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">K. Kuznetsov, R. Lambert, J. F. Rey. Endoscopy, 38, N 1 (2006) 76-81</mixed-citation><mixed-citation xml:lang="en">K. Kuznetsov, R. Lambert, J. F. Rey. Endoscopy, 38, N 1 (2006) 76-81</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">S. Tanaka, Y. Sano. Dig. Endosc., 23, Suppl. 1 (2011) 131-139</mixed-citation><mixed-citation xml:lang="en">S. Tanaka, Y. Sano. Dig. Endosc., 23, Suppl. 1 (2011) 131-139</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">H. Osawa, H. Yamamoto. Dig. Endosc., 26, Suppl. 1 (2014) 105-115</mixed-citation><mixed-citation xml:lang="en">H. Osawa, H. Yamamoto. Dig. Endosc., 26, Suppl. 1 (2014) 105-115</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">S. V.Patwardhan. Reflectance Imaging and Analysis for Evaluating Tissue Pigmentation, patent US 2011/0206254 A1</mixed-citation><mixed-citation xml:lang="en">S. V.Patwardhan. Reflectance Imaging and Analysis for Evaluating Tissue Pigmentation, patent US 2011/0206254 A1</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">I. Nishidate, T. Maeda, K. Niizeki, Y. Aizu. Sensors, 13, N 6 (2013) 7902-7915</mixed-citation><mixed-citation xml:lang="en">I. Nishidate, T. Maeda, K. Niizeki, Y. Aizu. Sensors, 13, N 6 (2013) 7902-7915</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">R. Jolivot, Y. Benezeth, F. Marzani. Int. J. Biomed. Imag., 2013 (2013) ID 978289 (15 p.)</mixed-citation><mixed-citation xml:lang="en">R. Jolivot, Y. Benezeth, F. Marzani. Int. J. Biomed. Imag., 2013 (2013) ID 978289 (15 p.)</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">С. А. Лысенко, М. М. Кугейко. Измерит. техн., № 6 (2013) 67-72 [S. A. Lisenko, M. M. Kugeiko. Measur. Tech., 56, N 6 (2013) 721-729]</mixed-citation><mixed-citation xml:lang="en">С. А. Лысенко, М. М. Кугейко. Измерит. техн., № 6 (2013) 67-72 [S. A. Lisenko, M. M. Kugeiko. Measur. Tech., 56, N 6 (2013) 721-729]</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">A. N. Bashkatov, E. A. Genina, V. V. Tuchin. J. Innovative Opt. Health Sci., 4, N 1 (2011) 9-38</mixed-citation><mixed-citation xml:lang="en">A. N. Bashkatov, E. A. Genina, V. V. Tuchin. J. Innovative Opt. Health Sci., 4, N 1 (2011) 9-38</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">J. Qu, C. MacAulay, S. Lam, B. Palcic. Appl. Opt., 33, N 31 (1994) 7397-7405</mixed-citation><mixed-citation xml:lang="en">J. Qu, C. MacAulay, S. Lam, B. Palcic. Appl. Opt., 33, N 31 (1994) 7397-7405</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">G. Zonios, L. T. Perelman, V. Backman, R. Manoharan, M. Fitzmaurice, J. Van Dam, M. S. Feld. Appl. Opt., 38, N 31 (1999) 6628-6637</mixed-citation><mixed-citation xml:lang="en">G. Zonios, L. T. Perelman, V. Backman, R. Manoharan, M. Fitzmaurice, J. Van Dam, M. S. Feld. Appl. Opt., 38, N 31 (1999) 6628-6637</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">P. R. Bargo, S. A. Prahl, T. T. Goodell, R. A. Sleven, G. Koval, G. Blair, S. L. Jacques. J. Biomed. Opt., 10, N 3 (2005) 034018-1-034018-15</mixed-citation><mixed-citation xml:lang="en">P. R. Bargo, S. A. Prahl, T. T. Goodell, R. A. Sleven, G. Koval, G. Blair, S. L. Jacques. J. Biomed. Opt., 10, N 3 (2005) 034018-1-034018-15</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">H. J. Wei, D. Xing, J. J. Lu, H. M. Gu, G. Y. Wu, Y. Jin. World J. Gastroenterol., 11, N 16 (2005) 2413-2419</mixed-citation><mixed-citation xml:lang="en">H. J. Wei, D. Xing, J. J. Lu, H. M. Gu, G. Y. Wu, Y. Jin. World J. Gastroenterol., 11, N 16 (2005) 2413-2419</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">J. W. Spliethoff, D. J. Evers, H. M. Klomp, J. W. van Sandick, M. W. Wouters, R. Nachabe, G. W. Lucassen, B. H. W. Hendriks, J. Wesseling, T. J. M. Ruers. Lung Cancer, 80, N 2 (2013) 165-171</mixed-citation><mixed-citation xml:lang="en">J. W. Spliethoff, D. J. Evers, H. M. Klomp, J. W. van Sandick, M. W. Wouters, R. Nachabe, G. W. Lucassen, B. H. W. Hendriks, J. Wesseling, T. J. M. Ruers. Lung Cancer, 80, N 2 (2013) 165-171</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">S. L. Jacques. Phys. Med. Biol., 58, N 11 (2013) R37-R61</mixed-citation><mixed-citation xml:lang="en">S. L. Jacques. Phys. Med. Biol., 58, N 11 (2013) R37-R61</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">С. А. Лысенко, М. М. Кугейко. Измерит. техн., N 11 (2013) 68-73</mixed-citation><mixed-citation xml:lang="en">С. А. Лысенко, М. М. Кугейко. Измерит. техн., N 11 (2013) 68-73</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">С. А. Лысенко. Квант. электрон., 43, N 8 (2013) 777-784</mixed-citation><mixed-citation xml:lang="en">С. А. Лысенко. Квант. электрон., 43, N 8 (2013) 777-784</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Y. Fawzy, S. Lam, H. Zeng. Biomed. Opt. Express, 6, N 8 (2015) 2980-2990</mixed-citation><mixed-citation xml:lang="en">Y. Fawzy, S. Lam, H. Zeng. Biomed. Opt. Express, 6, N 8 (2015) 2980-2990</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Principles and Practice of Interventional Pulmonology, Eds. A. Ernst, F. J. F. Herth, New York, Springer Science+Business Media (2013) 15-25</mixed-citation><mixed-citation xml:lang="en">Principles and Practice of Interventional Pulmonology, Eds. A. Ernst, F. J. F. Herth, New York, Springer Science+Business Media (2013) 15-25</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">W. Y. Cho, J. Y. Jang, D. H. Lee. Clin. Endosc., 44, N 2 (2011) 65-75</mixed-citation><mixed-citation xml:lang="en">W. Y. Cho, J. Y. Jang, D. H. Lee. Clin. Endosc., 44, N 2 (2011) 65-75</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Э. П. Зеге, А. П. Иванов, И. Л. Кацев. Перенос изображения в рассеивающей среде, Минск, Наука и техника (1985)</mixed-citation><mixed-citation xml:lang="en">Э. П. Зеге, А. П. Иванов, И. Л. Кацев. Перенос изображения в рассеивающей среде, Минск, Наука и техника (1985)</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">I. V. Meglinski, S. J. Matcher. Physiol. Measur., 23, N 4 (2002) 741-53</mixed-citation><mixed-citation xml:lang="en">I. V. Meglinski, S. J. Matcher. Physiol. Measur., 23, N 4 (2002) 741-53</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Y. Wang, Y. Gu, Z. Zuo, N. Huang. J. Biomed. Opt., 16, N 9 (2011) 098001-1-098001-8</mixed-citation><mixed-citation xml:lang="en">Y. Wang, Y. Gu, Z. Zuo, N. Huang. J. Biomed. Opt., 16, N 9 (2011) 098001-1-098001-8</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">M. Milanic, B. Majaron. J. Biomed. Opt., 16, N 12 (2011) 128002-1-128002-12</mixed-citation><mixed-citation xml:lang="en">M. Milanic, B. Majaron. J. Biomed. Opt., 16, N 12 (2011) 128002-1-128002-12</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">T. J. Pfefer, J. K. Barton, E. K. Chan, M. G. Ducros, B. S. Sorg, T. E. Milner, J. S. Nelson, A. J. Welch. EEE J. Selected Topics in Quantum Electron., 2, N 4 (1996) 934-942</mixed-citation><mixed-citation xml:lang="en">T. J. Pfefer, J. K. Barton, E. K. Chan, M. G. Ducros, B. S. Sorg, T. E. Milner, J. S. Nelson, A. J. Welch. EEE J. Selected Topics in Quantum Electron., 2, N 4 (1996) 934-942</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">http://www.gmp.ch/htmlarea/pdf/asahi_pdf/max302.pdf</mixed-citation><mixed-citation xml:lang="en">http://www.gmp.ch/htmlarea/pdf/asahi_pdf/max302.pdf</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">http://www.unibrain.com/wp-content/uploads/2013/04/ICX285AQ.pdf</mixed-citation><mixed-citation xml:lang="en">http://www.unibrain.com/wp-content/uploads/2013/04/ICX285AQ.pdf</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">http://www.medical-enc.ru/m/2/bronhi-anatomiya-gistologiya.shtml</mixed-citation><mixed-citation xml:lang="en">http://www.medical-enc.ru/m/2/bronhi-anatomiya-gistologiya.shtml</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">J. Qu, C. E. MacAulay, S. Lam, B. Palcic. Opt. Eng., 34, N 11 (1995) 3334-3343</mixed-citation><mixed-citation xml:lang="en">J. Qu, C. E. MacAulay, S. Lam, B. Palcic. Opt. Eng., 34, N 11 (1995) 3334-3343</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">M. Friebel, A. Roggan, G. Müller, M. Meinke. J. Biomed. Opt., 11, N 3 (2006) 34021-1-34021-10</mixed-citation><mixed-citation xml:lang="en">M. Friebel, A. Roggan, G. Müller, M. Meinke. J. Biomed. Opt., 11, N 3 (2006) 34021-1-34021-10</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">М. Friebel, М. Meinke. Appl. Opt., 45, N 12 (2006) 2838-2848</mixed-citation><mixed-citation xml:lang="en">М. Friebel, М. Meinke. Appl. Opt., 45, N 12 (2006) 2838-2848</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">А. Н. Башкатов, Д. М. Жестков, Э. А. Генина, В. В. Тучин. Опт. и спектр., 98, N 4 (2005) 695-703</mixed-citation><mixed-citation xml:lang="en">А. Н. Башкатов, Д. М. Жестков, Э. А. Генина, В. В. Тучин. Опт. и спектр., 98, N 4 (2005) 695-703</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
