zhpsЖурнал прикладной спектроскопииZhurnal Prikladnoii Spektroskopii0514-7506B. I. Stepanov Institute of Physics of the National Academy of Scienceszhps-867Research ArticleСтатьиПерспективы доклинического простого спектроскопического подхода к обнаружению COVID-19A nonclinical spectroscopic approach for diagnosing covid-19: a concise perspectiveMirJ. M.MirJ. M.

Awantipora, J&K, India-192122

Джабалпур

Awantipora, J&K, India-192122

Jabalpur-MP

mirjanmohammad@gmail.comKhanM. W.KhanM. W.

Джабалпур

Jabalpur-MP

ShallaA. H.ShallaA. H.

Awantipora, J&K, India-192122

Awantipora, J&K, India-192122

MauryaR. C.MauryaR. C.

Джабалпур

Jabalpur-MP

Исламский университет науки и техники: Университет RDDepartment of Chemistry, Islamic University of Science and Technology; Coordination, Metallopharmaceutical and Computational Chemistry Laboratory, Department of PG Studies and Research in Chemistry and Pharmacy, RD UniversityУниверситет RDCoordination, Metallopharmaceutical and Computational Chemistry Laboratory, Department of PG Studies and Research in Chemistry and Pharmacy, RD UniversityИсламский университет науки и техникиDepartment of Chemistry, Islamic University of Science and Technology202123072021884587593Copyright © Mir J.M., Khan M.W., Shalla A.H., Maurya R.C., 20212021Mir J.M., Khan M.W., Shalla A.H., Maurya R.C.Mir J.M., Khan M.W., Shalla A.H., Maurya R.C.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://zhps.ejournal.by/jour/article/view/867

В связи со вспышкой коронавирусной инфекции (COVID-19) перед научным миром встала задача разработки высокочувствительного и быстрого метода ее диагностики. Диагностическое тестирование, лечение и разработка вакцины от этой инфекции привлекают особое внимание научного сообщества. В настоящее время обнаружение/диагностика COVID-19 на основе полимеразной цепной реакции (ПЦР) является дорогостоящим и недостаточно надежным методом. Кроме того, этот метод требует длительного времени для получения результатов. В качестве эффективной методологии обнаружения COVID-19 предлагаются спектроскопические методы — комбинационного рассеяния света, инфракрасной спектроскопии и масс-спектрометрии.

With the COVID-19 outbreak, many challenges are posed before the scientific world to curb this pandemic. The diagnostic testing, treatment, and vaccine development for this infection caught the scientific community's immediate attention. Currently, despite the global proliferation of COVID-19 vaccination, the specific treatment for this disease is yet unknown. Meanwhile, COVID-19 detection or diagnosis using polymerase chain reaction (PCR)-based methods is expensive and less reliable. Moreover, this technique needs much time to furnish the results. Thus, the elaboration of a highly sensitive and fast method of COVID-19 diagnostics is of great importance. The spectroscopic approach is herein suggested as an efficient detection methodology for COVID-19 diagnosis, particularly Raman spectroscopy, infrared spectroscopy, and mass spectrometry. 

COVID-19коронавирусполимеразная цепная реакцияспектроскопияCOVID-19coronaviruspolymerase chain reactionspectroscopyReferencesM. A. Shereen, S. Khan, A. Kazmi, N. Bashir, R. Siddique, J. Adv. Res., 24, 91–98 (2020).M. A. Shereen, S. Khan, A. Kazmi, N. Bashir, R. Siddique, J. Adv. Res., 24, 91–98 (2020).Y. Zhu, C. Wang, L. Dong, M. Xiao, Brain. Behav. Immunol., 87, 142–143 (2020).Y. Zhu, C. Wang, L. Dong, M. Xiao, Brain. Behav. Immunol., 87, 142–143 (2020).B. Russell, C. Moss, A. Rigg, M. Van Hemelrijck, Ecancer Med. Sci., 14, 1023 (2020).B. Russell, C. Moss, A. Rigg, M. Van Hemelrijck, Ecancer Med. Sci., 14, 1023 (2020).P. Little, BMJ, 368, 1185 (2020).P. Little, BMJ, 368, 1185 (2020).B. Russell, C. Moss, G. George, A. Santaolalla, A. Cope, S. Papa, M. Van Hemelrijck, Ecancer Med. Sci., 14, 1022 (2020).B. Russell, C. Moss, G. George, A. Santaolalla, A. Cope, S. Papa, M. Van Hemelrijck, Ecancer Med. Sci., 14, 1022 (2020).J. Gao, Z. Tian, X. Yang, Biosci. Trends, 14, 72–73 (2020).J. Gao, Z. Tian, X. Yang, Biosci. Trends, 14, 72–73 (2020).A. Savarino, J. R. Boelaert, A. Cassone, G. Majori, R. Cauda, Lancet Infect. Dis., 3, 722–727 (2003).A. Savarino, J. R. Boelaert, A. Cassone, G. Majori, R. Cauda, Lancet Infect. Dis., 3, 722–727 (2003).Y. Yan, Z. Zou, Y. Sun, X. Li, K. F. Xu, Y. Wei, N. Jin, C. Jiang, Cell Res., 23, 300–302 (2013).Y. Yan, Z. Zou, Y. Sun, X. Li, K. F. Xu, Y. Wei, N. Jin, C. Jiang, Cell Res., 23, 300–302 (2013).A. Sternberg, D. L. McKee, C. Naujokat, Curr. Top. Med. Chem., 20, 1423–1433 (2020).A. Sternberg, D. L. McKee, C. Naujokat, Curr. Top. Med. Chem., 20, 1423–1433 (2020).L. L. Ferreira, A. D. Andricopulo, Curr. Top. Med. Chem., 20, 1577–1580 (2020).L. L. Ferreira, A. D. Andricopulo, Curr. Top. Med. Chem., 20, 1577–1580 (2020).W. Liu, H. L. Zhu, Y. Duan, Curr. Top. Med. Chem., 20, 603–605 (2020).W. Liu, H. L. Zhu, Y. Duan, Curr. Top. Med. Chem., 20, 603–605 (2020).C. M. Chu, V. C. C. Cheng, I. F. N. Hung, M. M. L. Wong, K. H. Chan, K. S. Chan, R. Y. T. Kao, L. L. M. Poon, C. L. P. Wong, Y. Guan, J. S. M. Peiris, K. Y. Yuen, Thorax, 59, 252–256 (2004).C. M. Chu, V. C. C. Cheng, I. F. N. Hung, M. M. L. Wong, K. H. Chan, K. S. Chan, R. Y. T. Kao, L. L. M. Poon, C. L. P. Wong, Y. Guan, J. S. M. Peiris, K. Y. Yuen, Thorax, 59, 252–256 (2004).R. S. Khan, I. U. Rehman, Expert Rev. Mol. Diagn., 20, 647–649 (2020).R. S. Khan, I. U. Rehman, Expert Rev. Mol. Diagn., 20, 647–649 (2020).K. Wu, R. Saha, D. Su, V. D. Krishna, J. Liu, M. C. Cheeran, J. P. Wang, arXiv preprint arXiv:2007.04809 2020, arXiv preprint arXiv:2007.04809.K. Wu, R. Saha, D. Su, V. D. Krishna, J. Liu, M. C. Cheeran, J. P. Wang, arXiv preprint arXiv:2007.04809 2020, arXiv preprint arXiv:2007.04809.S. Mahapatra, P. Chandra, Biosens. Bioelectron., 165, 112361 (2020).S. Mahapatra, P. Chandra, Biosens. Bioelectron., 165, 112361 (2020).C. Jenkins, B. Orsburn, BioRxiv (2020), https://doi.org/10.1101/2020.03.08.980383.C. Jenkins, B. Orsburn, BioRxiv (2020), https://doi.org/10.1101/2020.03.08.980383.L. F. D. C. de Silva, M. S. N. de Carvalho, Photodiagn. Photodyn. Ther., 30, 101765 (2020).L. F. D. C. de Silva, M. S. N. de Carvalho, Photodiagn. Photodyn. Ther., 30, 101765 (2020).G. Seo, G. Lee, M. J. Kim, S. H. Baek, M. Choi, K. B. Ku, C. S. Lee, S. Jun, D. Park, H. G. Kim, S. J. Kim, J. O. Lee, B. T. Kim, E. C. Park, S. J. Kim, ACS Nano, 14, 5135–5142 (2020).G. Seo, G. Lee, M. J. Kim, S. H. Baek, M. Choi, K. B. Ku, C. S. Lee, S. Jun, D. Park, H. G. Kim, S. J. Kim, J. O. Lee, B. T. Kim, E. C. Park, S. J. Kim, ACS Nano, 14, 5135–5142 (2020).I. Mahmud, T. J. Garrett, J. Am. Soc. Mass Spectrom., 31, 2013–2024 (2020).I. Mahmud, T. J. Garrett, J. Am. Soc. Mass Spectrom., 31, 2013–2024 (2020).C. Sheridan, Nat. Biotechnol., 38, 382–384 (2020).C. Sheridan, Nat. Biotechnol., 38, 382–384 (2020).B. A. Taha, Y. Al Mashhadany, M. H. Hafiz Mokhtar, M. S. Dzulkefly Bin Zan, N. Arsad, Sensors, 20, 6764 (2020).B. A. Taha, Y. Al Mashhadany, M. H. Hafiz Mokhtar, M. S. Dzulkefly Bin Zan, N. Arsad, Sensors, 20, 6764 (2020).J. M. Mir, N. Jain, P. S. Jaget, R. C. Maurya, Photodiagn. Photodyn. Ther., 19, 363–374 (2017).J. M. Mir, N. Jain, P. S. Jaget, R. C. Maurya, Photodiagn. Photodyn. Ther., 19, 363–374 (2017).J. M. Mir, N. Jain, P. S. Jaget, W. Khan, P. K. Vishwakarma, D. K. Rajak, B. A. Malik, R. C. Maurya, J. King Saud Univ. – Sci., 31, 89–100 (2019).J. M. Mir, N. Jain, P. S. Jaget, W. Khan, P. K. Vishwakarma, D. K. Rajak, B. A. Malik, R. C. Maurya, J. King Saud Univ. – Sci., 31, 89–100 (2019).J.M. Mir, R.C. Maurya, J. Chin. Adv. Mater. Soc., 6, 434–458 (2018).J.M. Mir, R.C. Maurya, J. Chin. Adv. Mater. Soc., 6, 434–458 (2018).J. M. Mir, B. A. Malik, R. C. Maurya, Rev. Inorg. Chem., 39, 91–112 (2019).J. M. Mir, B. A. Malik, R. C. Maurya, Rev. Inorg. Chem., 39, 91–112 (2019).J. M. Mir, R. C. Maurya, Rev. Inorg. Chem., 38, 193–220 (2018).J. M. Mir, R. C. Maurya, Rev. Inorg. Chem., 38, 193–220 (2018).R. C. Maurya, J. M. Mir, In: Advances in Metallodrugs: Preparation and Applications in Medicinal Chemistry, Wiley, New Jersey, 157–201 (2020).R. C. Maurya, J. M. Mir, In: Advances in Metallodrugs: Preparation and Applications in Medicinal Chemistry, Wiley, New Jersey, 157–201 (2020).J. M. Mir, R. C. Maurya, Annal. Ophthalmol. Visual Sci., 1003, 1–4 (2018).J. M. Mir, R. C. Maurya, Annal. Ophthalmol. Visual Sci., 1003, 1–4 (2018).R. C. Maurya, J. M. Mir, Int. J. Sci. Eng. Res., 5, 305–320 (2014).R. C. Maurya, J. M. Mir, Int. J. Sci. Eng. Res., 5, 305–320 (2014).J. M. Mir, S. A. Majid, A. H. Shalla, Rev. Inorg. Chem., 3493 (2021), doi.org/10.1515/revic-2020-0020.J. M. Mir, S. A. Majid, A. H. Shalla, Rev. Inorg. Chem., 3493 (2021), doi.org/10.1515/revic-2020-0020.J. M. Mir, R. C. Maurya, New J. Chem., 45, 1774–1784 (2021).J. M. Mir, R. C. Maurya, New J. Chem., 45, 1774–1784 (2021).J. M. Mir, R. C. Maurya, J. Biomol. Struct. Dyn. (2020), doi.org/10.1080/07391102.2020.1852969. A NONCLINICAL SPECTROSCOJ. M. Mir, R. C. Maurya, J. Biomol. Struct. Dyn. (2020), doi.org/10.1080/07391102.2020.1852969. A NONCLINICAL SPECTROSCOA. D. Whetton, G. W. Preston, S. Abubeker, N. Geifman, J. Proteome Res., 19, No. 11, 4219–4232 (2020).A. D. Whetton, G. W. Preston, S. Abubeker, N. Geifman, J. Proteome Res., 19, No. 11, 4219–4232 (2020).R. Singh, P. Su, L. Kimerling, A. Agarwal, B. W. Anthony, Appl. Phys. Lett., 113, No. 23, 231107 (2018), doi: arXiv:1806.06910v2.R. Singh, P. Su, L. Kimerling, A. Agarwal, B. W. Anthony, Appl. Phys. Lett., 113, No. 23, 231107 (2018), doi: arXiv:1806.06910v2.P. Chandra, Sensors Int., 1, 100019 (2020), doi.org/10.1016/j.sintl.2020.100019.P. Chandra, Sensors Int., 1, 100019 (2020), doi.org/10.1016/j.sintl.2020.100019.M. S. Nogueira, Photodiagn. Photodyn. Ther., 31, 101892 (2020).M. S. Nogueira, Photodiagn. Photodyn. Ther., 31, 101892 (2020).N. Rabiee, M. Bagherzadeh, A. Ghasemi, H. Zare, S. Ahmadi, Y. Fatahi, R. Dinarvand, M. Rabiee, S. Ramakrishna, M. R. Shokouhimehr, R. S. Varma, Int. J. Mol. Sci., 21, 5126 (2020), doi.org/10.3390/ijms21145126.N. Rabiee, M. Bagherzadeh, A. Ghasemi, H. Zare, S. Ahmadi, Y. Fatahi, R. Dinarvand, M. Rabiee, S. Ramakrishna, M. R. Shokouhimehr, R. S. Varma, Int. J. Mol. Sci., 21, 5126 (2020), doi.org/10.3390/ijms21145126.M. S. Nogueira, Photodiagn. Photodyn. Ther., 31, 101823 (2020).M. S. Nogueira, Photodiagn. Photodyn. Ther., 31, 101823 (2020).S. Pahlow, S. Meisel, D. Cialla-May, K. Weber, P. Rösch, J. Popp, Adv. Drug Deliv. Rev., 89, 105–120 (2015).S. Pahlow, S. Meisel, D. Cialla-May, K. Weber, P. Rösch, J. Popp, Adv. Drug Deliv. Rev., 89, 105–120 (2015).L. Jacobi, V. H. Damle, B. Rajeswaran, Y. R. Tischler, Roy. Soc. Open Sci., 7, 1–28 (2020).L. Jacobi, V. H. Damle, B. Rajeswaran, Y. R. Tischler, Roy. Soc. Open Sci., 7, 1–28 (2020).S. L. Manoto, A. El-Hussein, R. Malabi, L. Thobakgale, S. Ombinda-Lemboumba, Y. A. Attia, M. A. Kasem, P. Mthunzi-Kufa, Saudi J. Biol. Sci., 28, 78–89 (2021).S. L. Manoto, A. El-Hussein, R. Malabi, L. Thobakgale, S. Ombinda-Lemboumba, Y. A. Attia, M. A. Kasem, P. Mthunzi-Kufa, Saudi J. Biol. Sci., 28, 78–89 (2021).V. Deckert, T. Deckert-Gaudig, D. Cialla, J. Popp, R. Zell, A. V. Sokolov, Z. Yi, M. O. Scully, Med. Phys. (2020), doi: arXiv:2003.07951.V. Deckert, T. Deckert-Gaudig, D. Cialla, J. Popp, R. Zell, A. V. Sokolov, Z. Yi, M. O. Scully, Med. Phys. (2020), doi: arXiv:2003.07951.A. M. Elsharif, Int. J. Res. App. Sci. Eng. Technol., 8, 715–719 (2020).A. M. Elsharif, Int. J. Res. App. Sci. Eng. Technol., 8, 715–719 (2020).M. H. Jazayeri, H. Amani, A. A. Pourfatollah, H. Pazoki-Toroudi, B. Sedighimoghaddam, Sens. BioSens. Res., 9, 17–22 (2016).M. H. Jazayeri, H. Amani, A. A. Pourfatollah, H. Pazoki-Toroudi, B. Sedighimoghaddam, Sens. BioSens. Res., 9, 17–22 (2016).V. X. T. Zhao, T. I. Wong, X. T. Zheng, Y. N. Tan, X. Zhou, Mater. Sci. Energy Technol., 3, 237–249 (2020).V. X. T. Zhao, T. I. Wong, X. T. Zheng, Y. N. Tan, X. Zhou, Mater. Sci. Energy Technol., 3, 237–249 (2020).F. L. Martin, J. G. Kelly, V. Llabjani, P. L. Martin-Hirsch, I. I. Patel, J. Trevisan, N. J. Fullwood, M. J. Walsh, Nat. Protoc., 5, 1748–1760 (2010).F. L. Martin, J. G. Kelly, V. Llabjani, P. L. Martin-Hirsch, I. I. Patel, J. Trevisan, N. J. Fullwood, M. J. Walsh, Nat. Protoc., 5, 1748–1760 (2010).J. G. Kelly, J. Trevisan, A. D. Scott, P. L. Carmichael, H. M. Pollock, P. L. Martin-Hirsch, F. L. Martin, J. Proteome Res., 10, 1437–1448 (2011).J. G. Kelly, J. Trevisan, A. D. Scott, P. L. Carmichael, H. M. Pollock, P. L. Martin-Hirsch, F. L. Martin, J. Proteome Res., 10, 1437–1448 (2011).W. McIntyre, R. Netzband, G. Bonenfant, J. M. Biegel, C. Miller, G. Fuchs, E. Henderson, M. Arra, M. Canki, D. Fabris, C.T. Pager, Nucleic Acids Res., 46, 5776–5791 (2018).W. McIntyre, R. Netzband, G. Bonenfant, J. M. Biegel, C. Miller, G. Fuchs, E. Henderson, M. Arra, M. Canki, D. Fabris, C.T. Pager, Nucleic Acids Res., 46, 5776–5791 (2018).M. C. Santos, C. L. Morais, K. M. Lima, Biomed. Spectrosc. Imag., 9, 103–118 (2020).M. C. Santos, C. L. Morais, K. M. Lima, Biomed. Spectrosc. Imag., 9, 103–118 (2020).F. M. Nachtigall, A. Pereira, O. S. Trofymchuk, L. S. Santos, Nat. Biotechnol., 38, 1168–1173 (2020).F. M. Nachtigall, A. Pereira, O. S. Trofymchuk, L. S. Santos, Nat. Biotechnol., 38, 1168–1173 (2020).J. A. SoRelle, K. Patel, L. Filkins, J. Y. Park, Clin. Chem., 66, 1367–1368 (2020).J. A. SoRelle, K. Patel, L. Filkins, J. Y. Park, Clin. Chem., 66, 1367–1368 (2020).V. S. Raj, M. M. Lamers, S. L. Smits, J. A. Demmers, H. Mou, B. J. Bosch, B. L. Haagmans, In: Coronaviruses, Humana Press, New York, 165–182 (2015).V. S. Raj, M. M. Lamers, S. L. Smits, J. A. Demmers, H. Mou, B. J. Bosch, B. L. Haagmans, In: Coronaviruses, Humana Press, New York, 165–182 (2015).A. M. Zaki, S. Van Boheemen, T. M. Bestebroer, A. D. Osterhaus, R. A. Fouchier, N. Engl. J. Med., 367, 1814–1820 (2012).A. M. Zaki, S. Van Boheemen, T. M. Bestebroer, A. D. Osterhaus, R. A. Fouchier, N. Engl. J. Med., 367, 1814–1820 (2012).W. Li, M. J. Moore, N. Vasilieva, J. Sui, S. K. Wong, M. A. Berne, M. Somasundaran, J. L. Sullivan, K. Luzuriaga, T. C. Greenough, H. Choe, Nature, 426, 450–454 (2003).W. Li, M. J. Moore, N. Vasilieva, J. Sui, S. K. Wong, M. A. Berne, M. Somasundaran, J. L. Sullivan, K. Luzuriaga, T. C. Greenough, H. Choe, Nature, 426, 450–454 (2003).D. Gouveia, G. Miotello, F. Gallais, J. C. Gaillard, S. Debroas, L. Bellanger, J. P. Lavigne, A. Sotto, L. Greng, O. P. J. Armengaud, J. Proteome Res., 19, 4407–4416 (2020).D. Gouveia, G. Miotello, F. Gallais, J. C. Gaillard, S. Debroas, L. Bellanger, J. P. Lavigne, A. Sotto, L. Greng, O. P. J. Armengaud, J. Proteome Res., 19, 4407–4416 (2020).

The authors declare that there are no conflicts of interest present.