STUDY OF IR SPECTRA OF SALIVA OF PATIENTS WITH ONCOLOGIC DISEASES
Abstract
He principal possibility of the lung and breast cancer diagnosis by studying of saliva with the use of the method of infrared Fourier spectroscopy is shown. Statistically significant differences in the saliva IR spectra of patients with lung cancer are observed in the range of 1070-1240 cm- 1 , whereas for patients with breast cancer - they are observed in the whole studied spectral range. The coefficients I1398/ 1454 and I1240/ 1310 were revealed, the change of which on the background of oncological pathology are statistically significant. The intensity correlations of the saliva absorption bands in the IR spectra with non-specific biochemical parameters, which in general form characterize the enhancement of intoxication, inhibition of the antioxidant defense system and the immune response of the organism, were established. A promising area of research is the use of saliva IR spectroscopy to monitor the treatment process and control the occurrence of cancer recurrence.
About the Authors
L. V. Bel’Skaya
Omsk State Pedagogical University
Russian Federation
Russian Federation
E. A. Sarf
Omsk State Pedagogical University
Russian Federation
Russian Federation
I. A. Gundyrev
Tri-Soft
Russian Federation
Russian Federation
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Review
For citations:
Bel’Skaya L.V., Sarf E.A., Gundyrev I.A. STUDY OF IR SPECTRA OF SALIVA OF PATIENTS WITH ONCOLOGIC DISEASES. Zhurnal Prikladnoii Spektroskopii. 2018;85(6):952-961. (In Russ.)
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