Capabilities of Diffusion Spectroscopy with Spatial Resolution in Determining the Hydration and Parameters of the Microvasculature of Biotissues
Abstract
Using specific examples of recording and processing the spectral-spatial profiles of local diffuse reflection of light radiation by tissues of the human hand, the capabilities of spectroscopy with spatial resolution when determining the optical properties and parameters of the microvasculature of the circulatory system of superficial tissues are demonstrated. It is shown that the greatest contribution to the scatter of the obtained results is made by the heterogeneity of tissue properties caused by individual distribution of vessels and gradients of chromophore concentrations in the investigated point of the body, as well as by poor study of absorption indices of the main chromophores of exsanguinated and dehydrated subcutaneous tissue. The technique of registration of spectral-spatial profiles and their two-stage processing is presented, and its capabilities and disadvantages are discussed. Prospective application of diffuse reflection spectroscopy with spatial resolution in controlling the hydration of superficial tissues in the process of treatment of their inflammation and edema is shown.
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Review
For citations:
Firago V.A. Capabilities of Diffusion Spectroscopy with Spatial Resolution in Determining the Hydration and Parameters of the Microvasculature of Biotissues. Zhurnal Prikladnoii Spektroskopii. 2024;91(3):378-393. (In Russ.)