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Chromogenic Signaling Probes with Different “N, O” Donors for Fe3+ Sensing and Cell Imaging

Abstract

Iron, as the most prevalent critical trace element in the human body, is crucial for many basic physiological functions and has many environmental applications. Therefore, excellent chemosensors with high sensitivity and good selectivity toward iron are highly desired. Three new fluorescent colorimetric chemosensors (CS1, CS2, and CS3) were synthesized and prepared through a one-step reaction to selectively detect Fe3+ in aqueous media. To effectively coordinate metal ions, the sensors contain rhodamine derivatives with different “N, O” donor atoms. Of these sensors, CS2 and CS3 demonstrated sensing behavior and colorimetric “off-on” sensing for Fe3+ over various biologically important metal ions, rendering good selectivity. Fluorescent imaging was performed to confirm the possibility of applying the sensors in living cells.

About the Authors

M. Geng
College of Food and Biology, Changchun Polytechnic
China

Changchun, Jilin



C. Zhang
College of Food and Biology, Changchun Polytechnic
China

Changchun, Jilin



L. Yu
College of Food and Biology, Changchun Polytechnic
China

Changchun, Jilin



W. Wang
School of Mechanical Engineering, North China University of Water Resources and Electric Power
China

Zhengzhou



L. Liu
School of Materials Science and Engineering, Jiangsu University
China

Zhenjiang, Jiangsu



K.  Song
School of Life Science, Changchun Normal University
China

Changchun, Jilin



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Review

For citations:


Geng M., Zhang C., Yu L., Wang W., Liu L., Song K. Chromogenic Signaling Probes with Different “N, O” Donors for Fe3+ Sensing and Cell Imaging. Zhurnal Prikladnoii Spektroskopii. 2024;91(2):315. (In Russ.)

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ISSN 0514-7506 (Print)