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Spectral Investigations of Inclusion Complexes of the Bifluorophore Fluorescein with α-, β-, and γ-Cyclodextrins
Abstract
The formation of inclusion complexes of the (6-FAM)2 bifluorophore with α-, β-, and γ-cyclodextrins in a phosphate buffer solution (pH 9.0) was studied by spectrophotometry and fluorimetry. The association constants and Gibbs energy changes for 1:1 stoichiometry was determined. The highest association constant was observed for the complex with β-cyclodextrin, which is explained by the optimal spatial match between the guest molecule and the host’s cavity. The effect of the (6-FAM)2/β-CD inclusion complex on the fluorescent response of the system in the presence of protein (bovine serum albumin) is shown.
About the Authors
H. S. Pilipovich
B.I. Stepanov Institute of Physics of the National Academy of Sciences of Belarus
Belarus
Belarus
Minsk
F. Fan
Institute of Physical Organic Chemistry of the National Academy of Sciences of Belarus
Belarus
Belarus
Minsk
I. I. Lisenko
Institute of Physical Organic Chemistry of the National Academy of Sciences of Belarus
Belarus
Belarus
Minsk
V. A. Povedailo
B.I. Stepanov Institute of Physics of the National Academy of Sciences of Belarus
Belarus
Belarus
Minsk
S. A. Tikhomirov
B.I. Stepanov Institute of Physics of the National Academy of Sciences of Belarus
Belarus
Belarus
Minsk
V. V. Shmanai
Institute of Physical Organic Chemistry of the National Academy of Sciences of Belarus
Belarus
Belarus
Minsk
References
1. J. Zhang, D. Gabel, K. I. Assaf, W. M. Nau. Org. Lett., 24 (2022) 9184—9188
2. A. Kermagoret, D. Bardelang. Chem. Eur. J., 29 (2023) e202302114(1—18)
3. G. Yu, X. Zhou, Z. Zhang, C. Han, Z. Mao, C. Gao, F. Huang. J. Am. Chem. Soc., 134 (2012) 19489—19496
4. C. Wang, H. Li, J. Dong, Y. Chen, X. Luan, X. Li, X. Du. Chem. Eur. J., 28 (2022) e202202050
5. K. N. Houk, A. G. Leach, S. P. Kim, X. Zhang. Angew. Chem. Int. Ed., 42 (2003) 4872—4897
6. J. W. Steed, D. R. Turner, K. J. Wallace. Core Concepts in Supramolecular Chemistry and Nanochemistry, John Wiley & Sons (2007)
7. P. S. Stayton, S. Freitag, L. A. Klumb, A. Chilkoti, V. Chu, J. E. Penzotti, R. To, D. Hyre, I. Le Trong, T. P. Lybrand. Biomol. Eng., 16 (1999) 39—44
8. X. Chen, T. Pradhan, F. Wang, J. S. Kim, J. Yoon. Chem. Rev., 112 (2012) 1910—1956
9. R. Mejia-Ariza, L. Grana-Suarez, W. Verboom, J. Huskens. J. Mater. Chem., B 5 (2017) 36—52
10. L. Zhu, M. Zhu, Y. Zhao. Chem. Plus. Chem., 82 (2017) 30—41
11. С. С. Ануфрик, В. В. Тарковский, C. Н. Анучин. Опт. и спектр., 130 (2022) 1181—1192
12. L. Flamigni. J. Phys. Chem., 97 (1993) 9566—9572
13. L. N. Bogdanova, N. O. Mchedlov-Petrossyan, N. A. Vodolazkaya, A. V. Lebed. Carbohydrate Research, 345 (2010) 1882—1890
14. M. Malanga, A. Darcsi, M. Balint, G. Benkovics, T. Sohajda, S. Ben. Beilstein J. Org. Chem., 12 (2016) 537—548
15. S. Suganthi, A. Aleymma, S. P. Archana, M. Varnitha, V. Israel, Y. Sameena. J. Biomol. Struct. Dyn., 41 (2023) 3791—3796
16. V. A. Povedailo, I. L. Lysenko, S. A. Tikhomirov, D. L. Yakovlev, D. A. Tsybulsky, A. S. Kruhlik, F. Fan, Y. V. Martynenko-Makaev, O. L. Sharko, P. V. Duong, P. H. Minh, V. V. Shmanai. J. Fluoresc., 30, N 3 (2020) 629—635
17. A. Ryzhakov, T. D. Thi, J. Stappaerts, B. Bertoletti, K. Kimpe, A. R. Sá Couto, P. Saokham, G. Van den Mooter, P. Augustijns, G. W. Somsen, S. Kurkov, S. Inghelbrecht, A. Arien, M. I. Jimidar, K. Schrijnemakers, T. Loftsson. J. Pharm. Sci., 105 (2016) 2556—2569
18. B. G. Poulson, Q. A. Alsulami, Abeer Sharfalddin. Polysaccharides, 3 (2022) 1—31
19. F. Fan, V. A. Povedailo, I. L. Lysenko, O. L. Sharko, I. O. Mazunin, S. A. Tikhomirov, V. V. Shmanai. J. Appl. Spectr., 91, N 5 (2024) 1055—1064
Review
For citations:
Pilipovich H.S., Fan F., Lisenko I.I., Povedailo V.A., Tikhomirov S.A., Shmanai V.V. Spectral Investigations of Inclusion Complexes of the Bifluorophore Fluorescein with α-, β-, and γ-Cyclodextrins. Zhurnal Prikladnoii Spektroskopii. 2026;93(2):238-244. (In Russ.)
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