MODELING OF FIBER OPTIC PROBES FOR SELECTIVE REGISTRATION OF FLUORESCENCE OF MULTILAYERED BIOLOGICAL TISSUES
Abstract
We have modeled various configurations of fiber optic probes and analyzed the fluorescence spectra from a model of human skin tissue. The stochastic Monte Carlo method implemented in the TracePro software package is used to simulate the propagation of light in the tissue and optical fiber. Endogenous fluorophores-riboflavin and protoporphyrin IX serve as fluorescence sources of the skin model. They have a minimal intersection of the emission spectra and provide fluorescence of human skin when excited by laser radiation with a wavelength of 405 nm. The assumption about the possibility of selecting the fluorescence signal by the tissue depth using specific parameters of optical fiber probes is tested. For the first time, model spectra were obtained using six configurations of fiber optic probes for the selective recording of skin autofluorescence.
About the Authors
A. A. Shatskaya
S. P. Korolev Samara National Research University
Russian Federation
Russian Federation
Samara, 443086
D. N. Artemyev
S. P. Korolev Samara National Research University
Russian Federation
Russian Federation
Samara, 443086
I. A. Bratchenko
S. P. Korolev Samara National Research University
Russian Federation
Russian Federation
Samara, 443086
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Review
For citations:
Shatskaya A.A., Artemyev D.N., Bratchenko I.A. MODELING OF FIBER OPTIC PROBES FOR SELECTIVE REGISTRATION OF FLUORESCENCE OF MULTILAYERED BIOLOGICAL TISSUES. Zhurnal Prikladnoii Spektroskopii. 2020;87(1):130-139. (In Russ.)
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