Determination of the dynamics of the intracellular pool of zinc ions in human erythrocytes using a fluorescent probe FluoZin-3
Abstract
We demonstrate a biophysical approach for estimation of the dynamics of a labile pool of zinc ions in human erythrocytes in the range from 1 to 1000 nM using a FluoZin-3 fluorescent probe. This method can be used in biomedical research and become the basis for developing methods for diagnosing or predicting the disease course associated with failure in zinc metabolism.
About the Authors
Y. M. Harmaza
Institute of Biophysics and Cell Engineering of the National Academy of Sciences of Belarus
Belarus
Minsk, 220072.
Belarus
Minsk, 220072.
A. V. Tamashevski
Institute of Biophysics and Cell Engineering of the National Academy of Sciences of Belarus
Belarus
Minsk, 220072.
Belarus
Minsk, 220072.
E. I. Slobozhanina
Institute of Biophysics and Cell Engineering of the National Academy of Sciences of Belarus
Belarus
Minsk, 220072.
Belarus
Minsk, 220072.
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Review
For citations:
Harmaza Y.M., Tamashevski A.V., Slobozhanina E.I. Determination of the dynamics of the intracellular pool of zinc ions in human erythrocytes using a fluorescent probe FluoZin-3. Zhurnal Prikladnoii Spektroskopii. 2020;87(6):964-970. (In Russ.)
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